Obstetric and Neonatal Outcomes After Antipsychotic Medication Exposure in Pregnancy
Antipsychotic medications, which are first-line
treatments for psychotic and bipolar manic episodes, are frequently used by
women during childbearing years.1,2 More than half of women with severe mental
illness become pregnant,1,3,4 wherein offspring are often exposed to
antipsychotics while in utero.5 Medication, especially atypical antipsychotic,
use is on the rise in pregnant women with bipolar disorder, schizophrenia, and
unipolar depression as well as other psychiatric disorders.6 However, only
limited reproductive safety data are available on antipsychotic medications.
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